Formaldehyde → N-(Hydroxymethyl)-2-(thiophen-2-yl)acetamide

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

A mixture of 2-thienylacetamide, formaldehyde solution (37%, 1 equivalent) and a catalytic amount of potassium carbonate is warmed on a steam bath until a homogeneous solution is obtained. The solution is cooled to 0° C. overnight and the resulting solid collected by filtration.

Herkunft & Nachweise