1,4-Dihydro-2,6-dimethyl-4-(2-(trifluoromethyl)phenyl)-3,5-pyridinedicarboxylic acid diethyl ester → Ethyl 1,4,5,6-Tetrahydro-2-methyl-4-(2-trifluoromethylphenyl)-5-oxo-6-(2-pyridyl)-7-phenyl-1,6-naphthyridine-3-carboxylate
Reaktionsgleichung
[F:1][C:2]([F:28])([F:27])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[CH:9]1[C:14]([C:15]([O:17][CH2:18][CH3:19])=[O:16])=[C:13]([CH3:20])[NH:12][C:11]([CH3:21])=[C:10]1[C:22]([O:24]CC)=O.Cl.[N:30]1[CH:35]=[CH:34][CH:33]=[CH:32][C:31]=1[N:36]=[C:37](Cl)[C:38]1[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=1>>[CH3:20][C:13]1[NH:12][C:11]2[CH:21]=[C:37]([C:38]3[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=3)[N:36]([C:31]3[CH:32]=[CH:33][CH:34]=[CH:35][N:30]=3)[C:22](=[O:24])[C:10]=2[CH:9]([C:4]2[CH:5]=[CH:6][CH:7]=[CH:8][C:3]=2[C:2]([F:28])([F:1])[F:27])[C:14]=1[C:15]([O:17][CH2:18][CH3:19])=[O:16]Komponenten
3
Edukt 2
Produkt 1
Versuchsvorschrift
This product is obtained using the procedure of Example 1, from diethyl 1,4-dihydro-4-(2-trifluoromethylphenyl)2,6-dimethyl-3,5-pyridine dicarboxylate and N-(2-pyridyl)-benzimidoyl chloride HCl (2.5 g, 9.4%).