Methyl isothiocyanate → HCID 178432727, Verbindung
Reaktionsgleichung
[CH3:1][C:2]1[S:3][C:4]([C:8]([NH:10][NH2:11])=O)=[C:5]([CH3:7])[N:6]=1.[CH3:12][N:13]=[C:14]=[S:15]>C(O)C>[CH3:1][C:2]1[S:3][C:4]([C:8]2[N:13]([CH3:12])[C:14]([SH:15])=[N:11][N:10]=2)=[C:5]([CH3:7])[N:6]=1Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
To a 2,4-dimethylthiazole-5-carbohydrazide (Prep26, 23 g, 0.13 mol) in ethanol (100 ml), methyl isothiocyanate (49.1 g, 0.67 mol) was added. The mixture was refluxed overnight. Then the ethanol was partially removed under vacuum and the residue was filtered. The solid was dried under vacuum to afford 14 g of the title compound (y=46%).
Aufarbeitung
- temperatureThe mixture was refluxed overnight
- customThen the ethanol was partially removed under vacuum
- filtrationthe residue was filtered
- customThe solid was dried under vacuum
Quellen und Nachweise
- ORD-Eintrag
- ord-6a53f4a191fd4b9688199acb32574d83
- Quelldatensatz
- uspto-grants-2011_10
- Patentnummer
- US08030322B2
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