N-Boc-5-bromoindole → 5-{2-[(Tert-butoxycarbonyl-methyl-amino)-methyl]-phenylsulfanyl}-indole-1-carboxylic acid tert-butyl ester

Reaktionsgleichung

[C:1]([O:5][C:6](=[O:17])[N:7]([CH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[SH:16])[CH3:8])([CH3:4])([CH3:3])[CH3:2].C1(P(C2C=CC=CC=2)C2C=CC=CC=2OC2C=CC=CC=2P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.[C:57]([O:61][C:62]([N:64]1[C:72]2[C:67](=[CH:68][C:69](Br)=[CH:70][CH:71]=2)[CH:66]=[CH:65]1)=[O:63])([CH3:60])([CH3:59])[CH3:58].CC(C)([O-])C.[K+]>C1(C)C=CC=CC=1.[Pd].[Pd].C(=CC(C=CC1C=CC=CC=1)=O)C1C=CC=CC=1.C(=CC(C=CC1C=CC=CC=1)=O)C1C=CC=CC=1.C(=CC(C=CC1C=CC=CC=1)=O)C1C=CC=CC=1>[C:57]([O:61][C:62]([N:64]1[C:72]2[C:67](=[CH:68][C:69]([S:16][C:11]3[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=3[CH2:9][N:7]([C:6]([O:5][C:1]([CH3:4])([CH3:2])[CH3:3])=[O:17])[CH3:8])=[CH:70][CH:71]=2)[CH:66]=[CH:65]1)=[O:63])([CH3:60])([CH3:58])[CH3:59]