2-fluoro-4-(1H-1,2,4-triazol-1-yl)benzonitrile → (2-Fluoro-4-(1H-1,2,4-triazol-1-yl)phenyl)methanamine hydrochloride

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	2-fluoro-4-(1H-1,2,4-triazol-1-yl)benzonitrile	HCID 21069871	—
Edukt	(4-Fluoro-2-(1H-1,2,4-triazol-1-yl)phenyl)methanamine hydrochloride	HCID 21069882	—
Produkt	(2-Fluoro-4-(1H-1,2,4-triazol-1-yl)phenyl)methanamine hydrochloride	HCID 21069834	79%

Reaktionsschritte

This compound was prepared (79% yield) following the procedure for (4-fluoro-2-(1H-1,2,4-triazol-1-yl)phenyl)methanamine hydrochloride using (2-fluoro-4-(1H-1,2,4-triazol-1-yl)benzonitrile. 1H NMR (500 MHz, CD3OD) δ: 9.25 (1H, s), 8.46 (1H, s), 7.80 (1H, dd, J=8.6, 5.8 Hz), 7.64 (1H, dd, J=8.8, 2.4 Hz), 7.44 (1H, td, J=8.3, 2.6 Hz), 4.17 (2H, s). LCMS (M+H) calcd for C9H10N4F: 193.08; found: 193.16.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08039458B2
Quelldatensatz	uspto-grants-2011_10
ORD ID	ord-12049a6b3d8b4c8684a71fd5b0deabba
Quellennotiz	uspto-grants-2011_10