Hydrochloric Acid → 2-Hydroxy-4-methoxy-4-oxobutan-1-aminium chloride

Reaktionsgleichung

[ClH:1].[NH2:2][CH2:3][CH:4]([OH:9])[CH2:5][C:6]([OH:8])=[O:7].[CH3:10]O>>[Cl-:1].[OH:9][CH:4]([CH2:5][C:6]([O:8][CH3:10])=[O:7])[CH2:3][NH3+:2]

Komponenten

Edukt 3

HCID 313Hydrochloric Acid

HCID 887Methanol

HCID 21494-Amino-3-hydroxybutanoic acid

Produkt 1

HCID 866201242-Hydroxy-4-methoxy-4-oxobutan-1-aminium chloride

Versuchsvorschrift

Anhydrous hydrochloric acid gas was bubbled into a suspension of 4-amino-3-hydroxybutanoic acid (0.91 g, 7.61 mmol) in methanol (150 mL) until the solution was saturated and stirred at ambient temperature. After 18 h, the solution was concentrated to give the title compound (1.32 g). MS 134 (M+1).