3,3-Diphenylpyrrolidine → 1-{2-[3,3-Bis(4-fluorophenyl)pyrrolidin-1-yl]-2-oxoethyl}-3,3-diphenylpyrrolidin-2-one

Beteiligte Stoffe

Reaktionsschritte

The title compound was prepared using the procedure described in Example 172 substituting 2-(2-oxo-3,3-diphenylpyrrolidin-1-yl)acetic acid from Example 1C for 2-(3,3-bis(4-fluorophenyl)-2-oxopiperidin-1-yl)acetic acid and 3,3-bis(4-fluorophenyl)pyrrolidine from Example 203A for 3,3-diphenylpyrrolidine. 1H NMR (300 MHz, CDCl3) δ ppm 7.44-6.86 (m, 18H), 4.27-3.98 (m, 4H), 3.55 (dq, J=6.7, 9.6, 3H), 3.41 (t, J=6.7, 1H), 2.82 (q, J=6.5, 2H), 2.50 (dt, J=6.8, 21.3, 2H); MS (DCI) m/z 537.2 (M+H)+.

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