tert-butyl {2-[[(7R)-14-cyclohexyl-11-[({[(2,2-dimethoxyethyl)(methyl)amino]-sulfonyl}amino)carbonyl]-3-(pyridin-2-ylmethoxy)-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocin-7-yl](methyl)amino]ethyl}methylcarbamate → (7R)-14-cyclohexyl-7-{methyl[2-(methylamino)ethyl]amino}-N-{[methyl(2-oxoethyl)amino]sulfonyl}-3-(pyridin-2-ylmethoxy)-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxamide

Reaktionsgleichung

[CH:1]1([C:7]2[C:8]3[CH:9]=[CH:10][C:11]([C:47]([NH:49][S:50]([N:53]([CH2:55][CH:56](OC)[O:57]C)[CH3:54])(=[O:52])=[O:51])=[O:48])=[CH:12][C:13]=3[N:14]3[C:21]=2[C:20]2[CH:22]=[CH:23][C:24]([O:26][CH2:27][C:28]4[CH:33]=[CH:32][CH:31]=[CH:30][N:29]=4)=[CH:25][C:19]=2[O:18][CH2:17][C@H:16]([N:34]([CH3:46])[CH2:35][CH2:36][N:37](C)[C:38](=O)OC(C)(C)C)[CH2:15]3)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1>C(Cl)Cl.O.C(O)(C(F)(F)F)=O>[CH:1]1([C:7]2[C:8]3[CH:9]=[CH:10][C:11]([C:47]([NH:49][S:50]([N:53]([CH3:54])[CH2:55][CH:56]=[O:57])(=[O:51])=[O:52])=[O:48])=[CH:12][C:13]=3[N:14]3[C:21]=2[C:20]2[CH:22]=[CH:23][C:24]([O:26][CH2:27][C:28]4[CH:33]=[CH:32][CH:31]=[CH:30][N:29]=4)=[CH:25][C:19]=2[O:18][CH2:17][C@H:16]([N:34]([CH3:46])[CH2:35][CH2:36][NH:37][CH3:38])[CH2:15]3)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1