Cyclohexanone, 4,4-dimethyl- → (3S)-3-{cyclohexyl[(N-BOC)aminoacetyl]amino}pyrrolidine
Reaktionsgleichung
CC1(C)CCC(=O)CC1.C([N:20]1[CH2:24][CH2:23][C@H:22]([N:25]([CH:37]2[CH2:42][CH2:41][CH2:40][CH2:39][CH2:38]2)[C:26](=[O:36])[CH2:27][NH:28][C:29]([O:31][C:32]([CH3:35])([CH3:34])[CH3:33])=[O:30])[CH2:21]1)(OCC1C=CC=CC=1)=O>>[CH:37]1([N:25]([C:26](=[O:36])[CH2:27][NH:28][C:29]([O:31][C:32]([CH3:34])([CH3:33])[CH3:35])=[O:30])[C@H:22]2[CH2:23][CH2:24][NH:20][CH2:21]2)[CH2:38][CH2:39][CH2:40][CH2:41][CH2:42]1Komponenten
3
Versuchsvorschrift
The title compound was prepared following the procedure described in Step B of Intermediate 3 using the product of Step A, (3S)-1-Cbz-3-{cyclohexyl[(N-BOC)aminoacetyl]amino}pyrrolidine.
Quellen und Nachweise
- ORD-Eintrag
- ord-5f4dfa51f0e34005a050472857726974
- Quelldatensatz
- uspto-grants-2011_08