Tert-butyl (2-oxo-2,3-dihydrobenzimidazol-1-yl)acetate → [3-(2-Methoxy-2-oxoethyl)-4,6-dimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl]acetic acid

HRID 1675756Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1675756
O=C1N(CC(OC(C)(C)C)=O)C2C=CC=CC=2N1.C([O:23][C:24](=[O:43])[CH2:25][N:26]1[C:30]2[CH:31]=[C:32]([CH3:36])[CH:33]=[C:34]([CH3:35])[C:29]=2[N:28]([CH2:37][C:38]([O:40][CH3:41])=[O:39])[C:27]1=[O:42])(C)(C)C>>[CH3:41][O:40][C:38](=[O:39])[CH2:37][N:28]1[C:29]2[C:34]([CH3:35])=[CH:33][C:32]([CH3:36])=[CH:31][C:30]=2[N:26]([CH2:25][C:24]([OH:43])=[O:23])[C:27]1=[O:42]

Komponenten

3

Edukt 2

HCID 20814117Tert-butyl (2-oxo-2,3-dihydrobenzimidazol-1-yl)acetateHCID 86607784tert-Butyl [3-(2-methoxy-2-oxoethyl)-4,6-dimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl]acetate

Produkt 1

HCID 18449372[3-(2-Methoxy-2-oxoethyl)-4,6-dimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl]acetic acid

Versuchsvorschrift

Essentially following the procedures described for Intermediate 7, but using tert-butyl [3-(2-methoxy-2-oxoethyl)-4,6-dimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl]acetate from Step C in place of tert-butyl (2-oxo-3-pyridin-2-yl-2,3-dihydro-1H-benzimidazol-1-yl)acetate, the title compound was prepared. MS: m/z=293 (M+1).

Quellen und Nachweise

ORD-Eintrag
ord-56a554181e27490c8669380d3a2df828
Quelldatensatz
uspto-grants-2011_08
Patentnummer
US08003792B2

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