(S)-tert-butyl-5-(nitrooxy)hexanoate → (S)-5-(nitrooxy)hexanoic acid

HRID 1676010Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1676010
C([O:5][C:6](=[O:16])[CH2:7][CH2:8][CH2:9][C@@H:10]([O:12][N+:13]([O-:15])=[O:14])[CH3:11])(C)(C)C>C(Cl)Cl>[N+:13]([O:12][C@@H:10]([CH3:11])[CH2:9][CH2:8][CH2:7][C:6]([OH:16])=[O:5])([O-:15])=[O:14]

Komponenten

3

Edukt 1

HCID 58231672(S)-tert-butyl-5-(nitrooxy)hexanoate

Produkt 1

HCID 58231663(S)-5-(nitrooxy)hexanoic acid

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

(S)-tert-butyl-5-(nitrooxy)hexanoate (590 mg, 2.53 mmol), was dissolved in CH2Cl2 (20 mL). HClgas was bubbled into the solution until the disappearance of the starting material. The solution was reduced to a small volume and diluted in CH2Cl2 few times to remove residual acidity, then used without further purification.

Aufarbeitung

  1. customHClgas was bubbled into the solution until the disappearance of the starting material
  2. additiondiluted in CH2Cl2 few times
  3. customto remove residual acidity
  4. customused without further purification

Quellen und Nachweise

ORD-Eintrag
ord-484fde50b49a4e15a7d1d02cdd4e4e35
Quelldatensatz
uspto-grants-2011_08
Patentnummer
US08003811B2

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