N-methyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)aniline → [2-(4-Methylamino-phenyl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]-(1-methyl-cyclohexyl)-methanone

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	N-methyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)aniline	HCID 11957892	—
Edukt	(2-bromo-5H-pyrrolo[2,3-b]pyrazin-7-yl)-(1-methyl-cyclohexyl)-methanone	HCID 44199730	—
Produkt	[2-(4-Methylamino-phenyl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]-(1-methyl-cyclohexyl)-methanone	HCID 59540838	—

Reaktionsschritte

[2-(4-Methylamino-phenyl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]-(1-methyl-cyclohexyl)-methanone was prepared starting from (2-bromo-5H-pyrrolo[2,3-b]pyrazin-7-yl)-(1-methyl-cyclohexyl)-methanone and methyl-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-amine following general procedures as described in these Examples. MP 273-275° C., M+H=349.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08008298B2
Quelldatensatz	uspto-grants-2011_08
ORD ID	ord-0634f7bd39f345fe8fe8c42bc1edad90
Quellennotiz	uspto-grants-2011_08