Trifluoroacetic acid → HCID 58629078, Verbindung

HRID 1678072Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1678072
FC(F)(F)C(O)=O.[O:8]=[C:9]([CH3:28])[CH2:10][O:11][C:12]1[CH:17]=[CH:16][C:15]([CH2:18][CH2:19][NH:20]C(=O)OC(C)(C)C)=[CH:14][CH:13]=1>C(Cl)Cl>[NH2:20][CH2:19][CH2:18][C:15]1[CH:16]=[CH:17][C:12]([O:11][CH2:10][C:9]([CH3:28])=[O:8])=[CH:13][CH:14]=1

Komponenten

4

Edukt 2

HCID 6422Trifluoroacetic acidHCID 67310057Tert-butyl 2-[4-(2-oxopropoxy)phenyl]ethylcarbamate

Produkt 1

HCID 58629078HCID 58629078, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

Step 2 Trifluoroacetic acid (0.56 mL, 7.3 mmol) was added to a solution of tert-butyl 2-[4-(2-oxopropoxy)phenyl]ethylcarbamate (216 mg, 0.74 mmol) in CH2Cl2 (4 mL). The reaction mixture was stirred for 3 hr at ambient temperature, and then reaction mixture was stripped of volatiles in vacuo. The residue (143 mg) was used without further purification.

Aufarbeitung

  1. customreaction mixture
  2. customThe residue (143 mg) was used without further purification

Quellen und Nachweise

ORD-Eintrag
ord-54d63711d7c34320824bf4bbf16b9e8e
Quelldatensatz
uspto-grants-2011_08
Patentnummer
US08008487B2

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