Methyl Ferulate → Methyl 3-(4-hydroxy-3-methoxyphenyl)propanoate

HRID 1678577

Reaktionsgleichung

Reaktionsgleichung von HRID 1678577
[OH:1][C:2]1[CH:7]=[CH:6][C:5](/[CH:8]=[CH:9]/[C:10]([O:12][CH3:13])=[O:11])=[CH:4][C:3]=1[O:14][CH3:15]>CO.[C].[Pd]>[OH:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][C:10]([O:12][CH3:13])=[O:11])=[CH:4][C:3]=1[O:14][CH3:15]

Komponenten

4

Edukt 1

HCID 5357283Methyl Ferulate

Produkt 1

HCID 523498Methyl 3-(4-hydroxy-3-methoxyphenyl)propanoateAusbeute 101,9 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 178418390HCID 178418390, VerbindungKatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

To a solution of methyl (E)-3-(4-hydroxy-3-methoxyphenyl)-2-propenoate (3.0 g, 14 mmol) in methanol (30 mL) was added 10% palladium carbon (50% water content, 0.20 g), and the mixture was stirred at room temperature for 4 hours under hydrogen atmosphere. The reaction solution was filtered, and then the filtrate was concentrated under reduced pressure to give the title compound (3.0 g, yield 97%) as an oily matter. The obtained compound was used in the next reaction without purification.

Aufarbeitung

  1. filtrationThe reaction solution was filtered
  2. concentrationthe filtrate was concentrated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-1c795cb626f94a5da44697cc230bba21
Quelldatensatz
uspto-grants-2011_08
Patentnummer
US08008525B2

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