Phenol → Phenyl hexanoate

HRID 1678977Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1678977
[C:1](Cl)(=[O:7])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].[C:9]1([OH:15])[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>N1C=CC=CC=1>[C:1]([O:15][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)(=[O:7])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6]

Komponenten

4

Edukt 2

HCID 996PhenolHCID 67340Hexanoyl chloride

Produkt 1

HCID 522678Phenyl hexanoateAusbeute 94,7 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1049PyridineLösungsmittel

Versuchsvorschrift

30 ml (0.22 mole) of hexanoyl chloride were added dropwise over 30 minutes with stirring and cooling on an ice bath to a solution of 18.8 g (0.2 mole) of phenol in 80 ml of anhydrous pyridine and then the reaction mixture stood at room temperature for 3 hours and was poured into ice water. The mixture was extracted with ether and the ether extracts were washed with water, dilute hydrochloric acid and with water, dried over magnesium sulfate and evaporated to dryness to obtain 36.4 g of phenyl hexanoate as a yellow oil.

Aufarbeitung

  1. extractionThe mixture was extracted with ether
  2. washthe ether extracts were washed with water, dilute hydrochloric acid and with water
  3. dry with materialdried over magnesium sulfate
  4. customevaporated to dryness

Quellen und Nachweise

ORD-Eintrag
ord-f49c262856cb4177bd41e988fbf8f852
Quelldatensatz
uspto-grants-1978_03
Patentnummer
US04078078

Notizen zur Reaktion

Wird geladen…