m-Chloroperbenzoic acid → 2-Methyl-5-nitropyridine N-oxide

HRID 1680460Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1680460
[N+:1]([C:4]1[CH:5]=[CH:6][C:7]([CH3:10])=[N:8][CH:9]=1)([O-:3])=[O:2].ClC1C=CC=C(C(OO)=[O:19])C=1>C(Cl)Cl>[N+:1]([C:4]1[CH:9]=[N+:8]([O-:19])[C:7]([CH3:10])=[CH:6][CH:5]=1)([O-:3])=[O:2]

Komponenten

4

Edukt 2

HCID 70297m-Chloroperbenzoic acidHCID 27945522-Methyl-5-nitropyridine

Produkt 1

HCID 127053092-Methyl-5-nitropyridine N-oxide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

2.5 g of 5-nitro-2-picoline are dissolved in 60 ml of methylene chloride and 4.05 g (20 m mole) of 85% m-chloroperbenzoic acid are added while stirring at room temperature. Stirring is continued overnight and the mixture is washed twice with aqueous sodium bicarbonate and then with water. It is dried, evaporated and the residue crystallized from acetonitrile, to yield the 5-nitro-2-picoline-N-oxide melting at 149°-153°.

Aufarbeitung

  1. stirringStirring
  2. washthe mixture is washed twice with aqueous sodium bicarbonate
  3. customIt is dried
  4. customevaporated
  5. customthe residue crystallized from acetonitrile

Quellen und Nachweise

ORD-Eintrag
ord-5c2c3dd16b1a40a7a718ab15c4821040
Quelldatensatz
uspto-grants-1981_06
Patentnummer
US04273779

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