Hydrochloric Acid → 4-Hydroxy-4-methylaminomethylpiperidine dihydrochloride

HRID 1681601Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1681601
[OH:1][C:2]1([CH2:13][NH:14][CH3:15])[CH2:7][CH2:6][N:5](C(OCC)=O)[CH2:4][CH2:3]1.[ClH:16]>>[ClH:16].[ClH:16].[OH:1][C:2]1([CH2:13][NH:14][CH3:15])[CH2:7][CH2:6][NH:5][CH2:4][CH2:3]1

Komponenten

3

Edukt 2

HCID 313Hydrochloric AcidHCID 19382193HCID 19382193, Verbindung

Produkt 1

HCID 193821784-Hydroxy-4-methylaminomethylpiperidine dihydrochloride

Versuchsvorschrift

3 g (13.9 mmol) of ethyl 4-hydroxy-4-methylaminomethylpiperidine-1-carboxylate are heated overnight under reflux with 30 ml of concentrated hydrochloric acid. The product is concentrated, and the crystals are stirred with acetone, filtered off with suction and dried in a vacuum desiccator over P4O10.

Aufarbeitung

  1. concentrationThe product is concentrated
  2. filtrationfiltered off with suction
  3. dry with materialdried in a vacuum desiccator over P4O10

Quellen und Nachweise

ORD-Eintrag
ord-6714f538daa4493bbd8bf2761f34f1d6
Quelldatensatz
uspto-grants-1992_12
Patentnummer
US05173484

Notizen zur Reaktion

Wird geladen…