Hydrochloric Acid → 4-Ethylaminomethyl-4-hydroxypiperidine dihydrochloride

HRID 1681605Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1681605
[CH2:1]([NH:3][CH2:4][C:5]1([OH:16])[CH2:10][CH2:9][N:8](C(OCC)=O)[CH2:7][CH2:6]1)[CH3:2].[ClH:17]>>[ClH:17].[ClH:17].[CH2:1]([NH:3][CH2:4][C:5]1([OH:16])[CH2:6][CH2:7][NH:8][CH2:9][CH2:10]1)[CH3:2]

Komponenten

3

Edukt 2

HCID 313Hydrochloric AcidHCID 19382186HCID 19382186, Verbindung

Produkt 1

HCID 193821764-Ethylaminomethyl-4-hydroxypiperidine dihydrochloride

Versuchsvorschrift

4.6 g (20 mmol) of ethyl 4-ethylaminomethyl-4-hydroxypiperidine-1-carboxylate is heated overnight under reflux with 35 ml of concentrated hydrochloric acid. The product is concentrated, and the crystals are triturated with acetone, filtered off with suction and dried in a vacuum desiccator over P4O10.

Aufarbeitung

  1. concentrationThe product is concentrated
  2. customthe crystals are triturated with acetone
  3. filtrationfiltered off with suction
  4. dry with materialdried in a vacuum desiccator over P4O10

Quellen und Nachweise

ORD-Eintrag
ord-6f48121b7bdc4fdd935938eac7fa9b6d
Quelldatensatz
uspto-grants-1992_12
Patentnummer
US05173484

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