2-Chloro-1-(3,4,5-trimethoxyphenyl)ethan-1-one → HCID 54072957, Verbindung
Reaktionsgleichung
[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2([CH2:14][CH2:15][OH:16])[CH2:13][CH2:12][NH:11][CH2:10]2)[CH:5]=[CH:6][C:7]=1[Cl:8].[CH3:17][O:18][C:19]1[CH:20]=[C:21]([CH:26]=[C:27]([O:31][CH3:32])[C:28]=1[O:29][CH3:30])[C:22](=[O:25])[CH2:23]Cl>>[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2([CH2:14][CH2:15][OH:16])[CH2:13][CH2:12][N:11]([CH2:23][C:22]([C:21]3[CH:26]=[C:27]([O:31][CH3:32])[C:28]([O:29][CH3:30])=[C:19]([O:18][CH3:17])[CH:20]=3)=[O:25])[CH2:10]2)[CH:5]=[CH:6][C:7]=1[Cl:8]Komponenten
3
Versuchsvorschrift
Prepare by the method of example 3.1 using 2-[3-(3,4-dichloro-phenyl)-pyrrolidin-3-yl]-ethanol (2 mmol) and 3,4,5-trimethoxy-phenacyl chloride (2 mmol). Chromatograph on silica gel to give the title compound. Rf =0.45 (6% methanol/dichloromethane).
Quellen und Nachweise
- ORD-Eintrag
- ord-e705a6dd4e844dd4b7e5c824ed52727b
- Quelldatensatz
- uspto-grants-1997_06