Imidazole → 3-Benzoyl-4-(3,4-dimethoxyphenyl)-2-(1-imidazolylmethyl)-6,7-dimethoxyquinoline
Reaktionsgleichung
[C:1]([C:9]1[C:10]([CH2:33]Br)=[N:11][C:12]2[C:17]([C:18]=1[C:19]1[CH:24]=[CH:23][C:22]([O:25][CH3:26])=[C:21]([O:27][CH3:28])[CH:20]=1)=[CH:16][C:15]([O:29][CH3:30])=[C:14]([O:31][CH3:32])[CH:13]=2)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH:35]1[CH:39]=[CH:38][N:37]=[CH:36]1>>[C:1]([C:9]1[C:10]([CH2:33][C:36]2[NH:35][CH:39]=[CH:38][N:37]=2)=[N:11][C:12]2[C:17]([C:18]=1[C:19]1[CH:24]=[CH:23][C:22]([O:25][CH3:26])=[C:21]([O:27][CH3:28])[CH:20]=1)=[CH:16][C:15]([O:29][CH3:30])=[C:14]([O:31][CH3:32])[CH:13]=2)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1Komponenten
3
Versuchsvorschrift
According to the same manner as that described in Example 3, 3-benzoyl-2-bromomethyl-4-(3,4-dimethoxyphenyl)-6,7-dimethoxyquinoline was reacted with imidazole to give 3-benzoyl-4-(3,4-dimethoxyphenyl)-2-(1-imidazolylmethyl)-6,7-dimethoxyquinoline. This compound was recrystallized from ethanol to give colorless prisms. mp. 214°-215° C.
Quellen und Nachweise
- ORD-Eintrag
- ord-ac2278d0d0d6445d9725d45414cb8670
- Quelldatensatz