Ethanol → Acetic acid 2-amino-thiazol-4-ylmethyl ester

HRID 1685052Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1685052
Cl[CH2:2][C:3](=O)[CH2:4][OH:5].[NH2:7][C:8]([NH2:10])=[S:9].[CH3:11][CH2:12][OH:13]>>[NH2:7][C:8]1[S:9][CH:2]=[C:3]([CH2:4][O:5][C:12](=[O:13])[CH3:11])[N:10]=1

Komponenten

4

Edukt 3

HCID 702EthanolHCID 904941-Chloro-3-hydroxy-2-propanoneHCID 2723790Thiourea

Produkt 1

HCID 21915033Acetic acid 2-amino-thiazol-4-ylmethyl ester

Versuchsvorschrift

1-Chloro-3-hydroxy-propan-2-one (15.06 g) and thiourea (8.36 g) were dissolved in EtOH (55 mL) and heated at reflux over 30 min. The reaction mixture was concentrated under reduced pressure to afford the desired product.

Aufarbeitung

  1. temperatureheated
  2. temperatureat reflux over 30 min
  3. concentrationThe reaction mixture was concentrated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-fa3d1f2b4e6948d5999f82786c304316
Quelldatensatz
uspto-grants-2012_04
Patentnummer
US08148380B2

Notizen zur Reaktion

Wird geladen…