2-(3-(Hydroxymethyl)phenyl)ethanol → 3-(2-Hydroxyethyl)benzaldehyde

HRID 1689240Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1689240
[OH:1][CH2:2][C:3]1[CH:4]=[C:5]([CH2:9][CH2:10][OH:11])[CH:6]=[CH:7][CH:8]=1>C(Cl)Cl.[O-2].[O-2].[Mn+4]>[OH:11][CH2:10][CH2:9][C:5]1[CH:4]=[C:3]([CH:8]=[CH:7][CH:6]=1)[CH:2]=[O:1]

Komponenten

4

Edukt 1

HCID 579891802-(3-(Hydroxymethyl)phenyl)ethanol

Produkt 1

HCID 184247323-(2-Hydroxyethyl)benzaldehyde

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 178418406HCID 178418406, VerbindungKatalysatorHCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

Manganese (IV) dioxide (2.0 g) was added to a stirred solution of 2-(3-(hydroxymethyl)phenyl)ethanol (example 20, step a) (0.50 g) in DCM (10 mL) at room temperature. After 6 h, the reaction mixture was filtered through Celite eluting with DCM. The solution was evaporated in vacuo to give the subtitled compound as a gum. Used directly. Yield 0.46 g.

Aufarbeitung

  1. filtrationthe reaction mixture was filtered through Celite
  2. washeluting with DCM
  3. customThe solution was evaporated in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-b622e763ded94269b3aefdf4a5f3d3ce
Quelldatensatz
uspto-grants-2012_04
Patentnummer
US08148373B2

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