Pyrrolidine → HCID 86623311, Verbindung

HRID 1689725Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1689725
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([F:14])([F:13])[C:9]([F:12])([F:11])[F:10])=[CH:4][C:3]=1[N+:15]([O-:17])=[O:16].N1CCCC1.CO[CH:25](OC)[N:26]([CH3:28])[CH3:27]>C1(C)C=CC=CC=1>[CH3:25][N:26]([CH3:28])/[CH:27]=[CH:1]/[C:2]1[CH:7]=[CH:6][C:5]([C:8]([F:13])([F:14])[C:9]([F:12])([F:11])[F:10])=[CH:4][C:3]=1[N+:15]([O-:17])=[O:16]

Komponenten

5

Edukt 3

HCID 31268PyrrolidineHCID 78373Dimethylformamide dimethyl acetalHCID 542079941-Methyl-2-nitro-4-(pentafluoroethyl)benzene

Produkt 1

HCID 86623311HCID 86623311, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1140TolueneLösungsmittel

Versuchsvorschrift

To a solution of 1-methyl-2-nitro-4-(perfluoroethyl)benzene (10.0 g, 39.2 mmol) and pyrollidine (2.79 g, 39.2 mmol) in toluene (250 mL) was added dimethyl formamide dimethyl acetal (4.96 g, 39.2 mmol). The mixture was heated to reflux for 16 hours. After cooling to room temperature the mixture was concentrated under vacuum and the resulting oil was immediately used in the next reaction.

Aufarbeitung

  1. temperatureThe mixture was heated
  2. temperatureto reflux for 16 hours
  3. concentrationwas concentrated under vacuum
  4. customthe resulting oil was immediately used in the next reaction

Quellen und Nachweise

ORD-Eintrag
ord-e9a3670678bf4e35917e4a35389ea6ef
Quelldatensatz
uspto-grants-2012_04
Patentnummer
US08153622B2

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