Propionitrile → HCID 24991588, Verbindung

Reaktionsgleichung

C(#N)CC.[OH:5][CH2:6][CH2:7]C#N.[OH:10][CH2:11][CH:12]([C:15]1[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][CH:16]=1)[C:13]#[N:14]>>[C:6]([O:10][CH2:11][CH:12]([C:15]1[CH:16]=[CH:17][C:18]([Cl:21])=[CH:19][CH:20]=1)[C:13]#[N:14])(=[O:5])[CH3:7]

Komponenten

Edukt 3

HCID 7854Propionitrile

HCID 8011Hydracrylonitrile

HCID 66905586HCID 66905586, Verbindung

Produkt 1

HCID 24991588HCID 24991588, Verbindung

Versuchsvorschrift

This ester was prepared using the procedure described in Example 5, except 3-hydroxy-2-4-chlorophenyl)propanenitrile was used in place of 2-2-chloro-5-difluoromethoxy)phenyl)-3-hydroxypropanenitrile. The preparation of 3-hydroxy-2-(4-chlorophenyl)propanenitrile is described in Example 15. The recovered ester product was a colorless oil (79% yield).

Quellen und Nachweise

ORD-Eintrag: ord-cf1355e471d44010a1bf382b98483385
Quelldatensatz: uspto-grants-2012_04
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US08153688B2

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