Ethyl 4-hydrazinylbenzoate → ethyl 4-(5-amino-3-isopropyl-1H-pyrazol-1-yl)benzoate

Beteiligte Stoffe

Reaktionsschritte

Using the same method as Example A83, 4-hydrazinobenzoic acid ethyl ester (from Example A82, 3 g, 16.6 mmol) and 4-methyl-3-oxopentanenitrile (from Example A83, 2.7 g, 27.9 mmol) were combined to afford ethyl 4-(5-amino-3-isopropyl-1H-pyrazol-1-yl)benzoate (4 g, 88% yield), which was used to the next reaction without further purification.

Herkunft & Nachweise