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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1697719Erstellt: 26. Oktober 2026

Lithium Hydroxide → 5-(4-tert-Butylphenyl)-4-(phenylsulfonyl)pyrrolidine-2-carboxylic Acid

https://huagongshe.com/reaction/1697719

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktLithium HydroxideHCID 3939—
Edukt5-(4-tert-Butylphenyl)-4-(phenylsulfonyl)pyrrolidine-2-carboxylic Acid Ethyl EsterHCID 66770828—
Produkt5-(4-tert-Butylphenyl)-4-(phenylsulfonyl)pyrrolidine-2-carboxylic AcidHCID 66771182—

Reaktionsschritte

In analogy to the procedure described in example 253e, 5-(4-tert-butylphenyl)-4-(phenylsulfonyl)pyrrolidine-2-carboxylic acid ethyl ester was saponified in the presence of lithium hydroxide to give the title compound as colorless solid which was used in the next step without further purification. MS (ESI): m/z=388.2 [M+H]

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08163793B2
Quelldatensatzuspto-grants-2012_04
ORD IDord-14433362cc5e446a88da13f7ddbbfb03
Quellennotizuspto-grants-2012_04