Methyl 3-(2-chlorophenyl)propanoate → 3-(2-Chlorophenyl)propanoic acid

HRID 1701338

Reaktionsgleichung

Reaktionsgleichung von HRID 1701338
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][CH2:9][C:10]([O:12]C)=[O:11]>[OH-].[Na+]>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][CH2:9][C:10]([OH:12])=[O:11]

Komponenten

3

Edukt 1

HCID 18913495Methyl 3-(2-chlorophenyl)propanoate

Produkt 1

HCID 956763-(2-Chlorophenyl)propanoic acid

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 14798Sodium HydroxideLösungsmittel

Versuchsvorschrift

Methyl 3-(2-chlorophenyl)propionate was refluxed in 10% aqueous sodium hydroxide (1 l.) for two hours and the reaction mixture was cooled, acidified and filtered. The filter cake was dissolved in hot aqueous sodium bicarbonate and filtered. The filtrate was acidified and filtered to yield 3-(2-chlorophenyl)propionic acid.

Aufarbeitung

  1. temperaturethe reaction mixture was cooled
  2. filtrationfiltered
  3. dissolutionThe filter cake was dissolved in hot aqueous sodium bicarbonate
  4. filtrationfiltered
  5. filtrationfiltered

Quellen und Nachweise

ORD-Eintrag
ord-50b52fd89ee74f889f0ab0f9aeecf7b9
Quelldatensatz
uspto-grants-1980_03
Patentnummer
US04192888

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