Diethylamine → ethyl 5-(N,N-diethylaminomethyl)-2-furoate

HRID 1701800

Reaktionsgleichung

Reaktionsgleichung von HRID 1701800
Cl[CH2:2][C:3]1[O:7][C:6]([C:8]([O:10][CH2:11][CH3:12])=[O:9])=[CH:5][CH:4]=1.[CH2:13]([NH:15][CH2:16][CH3:17])[CH3:14]>C1C=CC=CC=1>[CH2:13]([N:15]([CH2:2][C:3]1[O:7][C:6]([C:8]([O:10][CH2:11][CH3:12])=[O:9])=[CH:5][CH:4]=1)[CH2:16][CH3:17])[CH3:14]

Komponenten

4

Edukt 2

HCID 8021DiethylamineHCID 263166Ethyl 5-(chloromethyl)-2-furancarboxylate

Produkt 1

HCID 20346154ethyl 5-(N,N-diethylaminomethyl)-2-furoate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 241BenzeneLösungsmittel

Versuchsvorschrift

Ethyl 5-(chloromethyl)-2-furoate (0.1 mole) is refluxed with diethylamine (0.25 mole) in 40 ml of benzene for one hour. The benzene solution is filtered off and washed with water. The organic layer is separated and dried over magnesium sulfate. The magnesium sulfate is removed by filtration and the organics are evaporated to dryness. The residue is distilled to give a pure fraction of ethyl 5-(N,N-diethylaminomethyl)-2-furoate boiling at 97°-106° C. at 0.1 mm of Hg.

Aufarbeitung

  1. filtrationThe benzene solution is filtered off
  2. washwashed with water
  3. customThe organic layer is separated
  4. dry with materialdried over magnesium sulfate
  5. customThe magnesium sulfate is removed by filtration
  6. customthe organics are evaporated to dryness
  7. distillationThe residue is distilled

Quellen und Nachweise

ORD-Eintrag
ord-3dc60f99f2a140ba89ca3e4738118d19
Quelldatensatz
uspto-grants-1980_03
Patentnummer
US04195023

Verknüpfte Notizen

Wird geladen…