Thionyl Chloride → HCID 178479468, Verbindung

HRID 1702609

Reaktionsgleichung

Reaktionsgleichung von HRID 1702609
[ClH:1].[NH:2]([CH2:6][C@H:7]1[CH2:12][CH2:11][C@H:10]([C:13]([OH:15])=O)[CH2:9][CH2:8]1)[C:3]([NH2:5])=[NH:4].S(Cl)([Cl:18])=O>>[ClH:18].[NH:2]([CH2:6][C@H:7]1[CH2:12][CH2:11][C@H:10]([C:13]([Cl:1])=[O:15])[CH2:9][CH2:8]1)[C:3]([NH2:5])=[NH:4]

Komponenten

3

Edukt 2

HCID 24386Thionyl ChlorideHCID 178479474HCID 178479474, Verbindung

Produkt 1

HCID 178479468HCID 178479468, Verbindung

Versuchsvorschrift

A suspension of trans-4-guanidinomethylcyclohexanecarboxylic acid hydrochloride (1.2 g) and thionyl chloride (15 ml) was stirred at room temperature for 3 hours. Thereafter, excess thionyl chloride was removed by distillation under reduced pressure. The residue was washed with anhydrous ethyl ether to obtain trans-4-guanidinomethylcyclohexanecarboxylic acid chloride hydrochloride (1.2 g) as colorless powder.

Aufarbeitung

  1. customThereafter, excess thionyl chloride was removed by distillation under reduced pressure
  2. washThe residue was washed with anhydrous ethyl ether

Quellen und Nachweise

ORD-Eintrag
ord-d9af0aa0853d4105a0fad7c3b8b7641c
Quelldatensatz
uspto-grants-1982_09
Patentnummer
US04348410

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