Hydrochloric Acid → 5-(Chloromethyl)uracil

HRID 1703050

Reaktionsgleichung

Reaktionsgleichung von HRID 1703050
O[CH2:2][C:3]1[C:4](=[O:10])[NH:5][C:6](=[O:9])[NH:7][CH:8]=1.[ClH:11]>>[Cl:11][CH2:2][C:3]1[C:4](=[O:10])[NH:5][C:6](=[O:9])[NH:7][CH:8]=1

Komponenten

3

Edukt 2

HCID 313Hydrochloric AcidHCID 781685-(Hydroxymethyl)uracil

Produkt 1

HCID 2361255-(Chloromethyl)uracil

Versuchsvorschrift

A solution of 1.4 g. (0.010 mole) of 5-hydroxymethyl uracil in 12.5 ml. of concentrated hydrochloric acid was prepared. A colorless precipitate (5-chloromethyl uracil) formed within two minutes and after about ten minutes the precipitate was collected by filtration, washed rapidly with ice cold water, dried and then suspended in 10 ml. of dimethylformamide.

Quellen und Nachweise

ORD-Eintrag
ord-4dcebf16c68b4e21871e38c7da8478f6
Quelldatensatz
uspto-grants-1982_09
Patentnummer
US04350754

Verknüpfte Notizen

Wird geladen…