Nitric Acid → 5-Methyl-2-n-propyl-4-imidazolecarboxaldehyde
Reaktionsgleichung
[CH3:1][C:2]1[NH:6][C:5]([CH2:7][CH2:8][CH3:9])=[N:4][C:3]=1[CH2:10][OH:11].[N+]([O-])(O)=O>>[CH3:1][C:2]1[NH:6][C:5]([CH2:7][CH2:8][CH3:9])=[N:4][C:3]=1[CH:10]=[O:11]Komponenten
3
Versuchsvorschrift
An 80 gm. portion of 5-methyl-2-n-propyl-4-imidazolemethanol is oxidized with 67.3 ml. of concentrated HNO3. A second portion of 101.4 gm. of the above compound is oxidized with 77 ml. of the acid. The reaction mixtures are combined, neutralized and worked up as in Example 25, giving the desired product, m.p. 126°-129° C.
Aufarbeitung
- customThe reaction mixtures
Quellen und Nachweise
- ORD-Eintrag
- ord-119bffd7f1ac4d869fe4c2608d56b312
- Quelldatensatz
- uspto-grants-1978_11
- Patentnummer
- US04124766
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