1,3-(Dihexyl)thiourea → 4-(4-Chloro-3-sulfamoylphenyl)-3-n-hexyl-2-n-hexylimino-1,3-thiazolidine-4-ol-hydrochloride
Reaktionsgleichung
[Cl:1][CH2:2][C:3]([C:5]1[CH:10]=[CH:9][C:8]([Cl:11])=[C:7]([S:12](=[O:15])(=[O:14])[NH2:13])[CH:6]=1)=[O:4].[CH2:16]([NH:22][C:23]([NH:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])=[S:24])[CH2:17][CH2:18][CH2:19][CH2:20][CH3:21]>>[ClH:1].[Cl:11][C:8]1[CH:9]=[CH:10][C:5]([C:3]2([OH:4])[CH2:2][S:24][C:23](=[N:22][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])[N:25]2[CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])=[CH:6][C:7]=1[S:12](=[O:15])(=[O:14])[NH2:13]Komponenten
3
Versuchsvorschrift
5.2 g of 2,4'-dichloro-3'-sulfamoylacetophenone and 4.8 g of 1,3-di-n-hexyl-thiourea were reacted according to the prescription given in Example 12, the end product was precipitated with diethyl ether and the remaining oil was treated with cyclohexane. Colorless, amorphous solid body: decomposition beginning at 75° C., γ C=N 1615 cm-1.
Aufarbeitung
- customthe end product was precipitated with diethyl ether
- additionthe remaining oil was treated with cyclohexane