N,N'-Dicyclopropylthiourea → 4-(4-Chloro-3-sulfamoylphenyl)-3-cyclopropyl-2-cyclopropylimino-1,3-thiazolidine-4-ol-hydrochloride

HRID 1703863Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1703863
[Cl:1][CH2:2][C:3]([C:5]1[CH:10]=[CH:9][C:8]([Cl:11])=[C:7]([S:12](=[O:15])(=[O:14])[NH2:13])[CH:6]=1)=[O:4].[CH:16]1([NH:19][C:20]([NH:22][CH:23]2[CH2:25][CH2:24]2)=[S:21])[CH2:18][CH2:17]1>>[ClH:1].[Cl:11][C:8]1[CH:9]=[CH:10][C:5]([C:3]2([OH:4])[CH2:2][S:21][C:20](=[N:19][CH:16]3[CH2:18][CH2:17]3)[N:22]2[CH:23]2[CH2:25][CH2:24]2)=[CH:6][C:7]=1[S:12](=[O:15])(=[O:14])[NH2:13]

Komponenten

3

Edukt 2

HCID 17750075N,N'-DicyclopropylthioureaHCID 213167492,4'-Dichloro-3'-sulfamoylacetophenone

Produkt 1

HCID 227605674-(4-Chloro-3-sulfamoylphenyl)-3-cyclopropyl-2-cyclopropylimino-1,3-thiazolidine-4-ol-hydrochloride

Versuchsvorschrift

5.2 g of 2,4'-dichloro-3'-sulfamoylacetophenone and 3.1 g of 1,3-dicyclopropylthiourea were reacted according to the prescription given in Example 12 and the colorless crystalline precipitate of the end product was filtered off.

Aufarbeitung

  1. filtrationthe colorless crystalline precipitate of the end product was filtered off

Quellen und Nachweise

ORD-Eintrag
ord-7690362a8793417196e056a245d8ffa9
Quelldatensatz
uspto-grants-1978_11
Patentnummer
US04125614

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