Methyl acetoacetate → 3-Furancarboxylic acid, 2,5-dimethyl-, methyl ester

HRID 1706338

Reaktionsgleichung

Reaktionsgleichung von HRID 1706338
[C:1]([O:4][CH:5]([CH3:8])[CH:6]=O)(=O)[CH3:2].[C:9]([O:15][CH3:16])(=[O:14])[CH2:10]C(C)=O>[Fe].CO>[CH3:16][O:15][C:9]([C:10]1[CH:6]=[C:5]([CH3:8])[O:4][C:1]=1[CH3:2])=[O:14]

Komponenten

5

Edukt 2

HCID 7757Methyl acetoacetateHCID 907282-(Acetyloxy)propanal

Produkt 1

HCID 802483-Furancarboxylic acid, 2,5-dimethyl-, methyl ester

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23925IronKatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

27 parts by weight of iron-III chloride and 149 parts by weight of 85.5 percent strength α-acetoxypropionaldehyde are added to a solution of 116 parts by weight of methyl acetoacetate in 120 parts by weight of methanol at a rate such that the mixture rises to the boil. The methanol is distilled off under atmospheric pressure and the product is then distilled under reduced pressure. 106.2 parts by weight of 2,5-dimethylfuran-3-carboxylic acid methyl ester, of boiling point 89° C./20 mbar, are obtained.

Aufarbeitung

  1. distillationThe methanol is distilled off under atmospheric pressure
  2. distillationthe product is then distilled under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-c8642babbd0f4c62b60da3f1892d1dd2
Quelldatensatz
uspto-grants-1980_06
Patentnummer
US04207243

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