Potassium Carbonate → HCID 13723675, Verbindung

HRID 1706691Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1706691
Br[CH:2]([CH2:8]Br)[C:3]([O:5][CH2:6][CH3:7])=[O:4].[CH3:10][C:11]1[CH:12]=[C:13]([OH:19])[C:14](=[CH:16][C:17]=1[CH3:18])[OH:15].C(=O)([O-])[O-].[K+].[K+]>CC(C)=O>[CH3:10][C:11]1[C:17]([CH3:18])=[CH:16][C:14]2[O:15][CH:2]([C:3]([O:5][CH2:6][CH3:7])=[O:4])[CH2:8][O:19][C:13]=2[CH:12]=1

Komponenten

5

Edukt 3

HCID 11430Potassium CarbonateHCID 97945Ethyl 2,3-dibromopropionateHCID 127302874,5-Dimethylbenzene-1,2-diol

Produkt 1

HCID 13723675HCID 13723675, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 180AcetoneLösungsmittel

Reaktionsbedingungen

Temperatur
30 °C

Versuchsvorschrift

86 g of ethyl 2,3-dibromopropionate was added, over a 15-minute period, to a stirred mixture of 41 g of 6A, 97 g of potassium carbonate and 300 ml of acetone. The temperature of the mixture rose to 60° C. The mixture was refluxed for 19 hours, cooled to 30° C. and filtered. The solvent was evaporated from the filtrate under reduced pressure. The residue was recrystallized from hexane to give 6, mp: 71°-72° C.

Aufarbeitung

  1. customrose to 60° C
  2. temperatureThe mixture was refluxed for 19 hours
  3. filtrationfiltered
  4. customThe solvent was evaporated from the filtrate under reduced pressure
  5. customThe residue was recrystallized from hexane
  6. customto give 6, mp: 71°-72° C.

Quellen und Nachweise

ORD-Eintrag
ord-e58108ecf2e148408ec945bc59295362
Quelldatensatz
uspto-grants-1980_06
Patentnummer
US04208424

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