Acetic Anhydride → 3-Hydroxy-3'-(trifluoromethyl)acrylophenone acetate

Beteiligte Stoffe

Reaktionsschritte

A suspension of 12.0 g. of 3-hydroxy-3'-(trifluoromethyl)acrylophenone sodium salt in 75 ml. of dioxane and 10 ml. of acetic anhydride is stirred at room temperature for 2 hours and then poured into water. The precipitate is collected by filtration, dissolved in methylene chloride and then passed through a hydrous magnesium silicate column and crystallized from methylene chloride-hexane to give the desired product, m.p. 55°-57° C.

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