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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1707645Erstellt: 26. Oktober 2026

1-[2-(4-Pyridinyl)ethyl]piperazine → 8-Chloro-10,11-dihydro-10-[[4-[2-(4-pyridinyl)ethyl]-1-piperazinyl]carbonyl]dibenz[b,f][1,4]oxazepine

https://huagongshe.com/reaction/1707645

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt1-[2-(4-Pyridinyl)ethyl]piperazineHCID 558685—
Edukt8-chlorodibenz[b,f][1,4]oxazepin-10(11H)carbonyl chlorideHCID 14975983—
Produkt8-Chloro-10,11-dihydro-10-[[4-[2-(4-pyridinyl)ethyl]-1-piperazinyl]carbonyl]dibenz[b,f][1,4]oxazepineHCID 15224926291,3%

Reaktionsschritte

The title compound of Example 2 (0.38 g, 1.3 mmol) was combined with the product of Example 88 (0.25 g, 1.3 mmol) and the reaction was carried out by the method of Example 4. Following chromatographic separation, 1.7 g of the white solid title product was obtained.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS05354747
Quelldatensatzuspto-grants-1994_10
ORD IDord-525a2e45e5144ec48c3316b67909b848
Quellennotizuspto-grants-1994_10