5-Acetoxyacetamido-3-methylcarbamoyl2,4,6-triiodobenzoyl chloride → N-(2,3-dihydroxypropyl)-5-[2,3-diacetoxypropionylamino)-N'-methyl-2,4,6-triiodoisophthalamide

HRID 1707905Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1707905
[C:1]([O:4][CH:5]([CH2:25][O:26][C:27](=[O:29])[CH3:28])[C:6]([NH:8]C1C(I)=C(C(=O)NC)C(I)=C(C=1I)C(Cl)=O)=[O:7])(=[O:3])[CH3:2].[OH:30][CH:31]([CH2:57][OH:58])[CH2:32][N:33](NC(=O)C)[C:34](=[O:52])[C:35]1[C:44]([I:45])=[C:43](OC(=O)C)[C:42]([I:50])=[C:37]([C:38]([NH:40][CH3:41])=[O:39])[C:36]=1[I:51].C(OCC(NC1C(I)=C(C(=O)NC)C(I)=C(C=1I)C(Cl)=O)=O)(=O)C>>[OH:30][CH:31]([CH2:57][OH:58])[CH2:32][NH:33][C:34](=[O:52])[C:35]1[C:44]([I:45])=[C:43]([NH:8][C:6](=[O:7])[CH:5]([O:4][C:1](=[O:3])[CH3:2])[CH2:25][O:26][C:27](=[O:29])[CH3:28])[C:42]([I:50])=[C:37]([C:38]([NH:40][CH3:41])=[O:39])[C:36]=1[I:51]

Komponenten

4

Edukt 3

HCID 156706225-Acetoxyacetamido-3-methylcarbamoyl2,4,6-triiodobenzoyl chlorideHCID 189602905-(2,3-Diacetoxypropionylamino)-3-methylcarbamoyl-2,4,6-triiodobenzoyl chlorideHCID 86748190N-(2,3-dihydroxypropyl)-5-acetoxy-acetamido-N'-methyl-2,4,6-triiodoisophthalamide

Produkt 1

HCID 86748189N-(2,3-dihydroxypropyl)-5-[2,3-diacetoxypropionylamino)-N'-methyl-2,4,6-triiodoisophthalamide

Versuchsvorschrift

Compound (12) is prepared from compound (11) in the same manner according to the procedure described for the preparation of compound (4) from compound (3) in Example I, C.

Quellen und Nachweise

ORD-Eintrag
ord-ac0a11267a894de5a74ba0a74983a8be
Quelldatensatz
uspto-grants-1994_10
Patentnummer
US05356613

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