Nitrogen mustard hydrochloride → 4-(2-Butoxyphenyl)-1-methylpiperazine

Beteiligte Stoffe

Reaktionsschritte

A stirred solution of 2-butoxybenzenamine (6.50 g) in chlorobenzene (50 ml) was treated with 2-chloro-N-(2-chloroethyl)-N-methylethanamine hydrochloride (7.70 g) according to the method of Intermediate 40. Concentration in vacuo of the dichloromethane extracts gave the title compound as a red oil (9.67 g).

Herkunft & Nachweise