HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Methyl-2-(2-Pyrazinyl)-1,3-Thiazole-5-Carbonyl Chloride → 1-[3-(3-ethoxy-4-methoxyphenyl)-5,6-dihydro-4H-pyridazin-1-yl]-1-(4-methyl-2-pyrazin-2-yl-thiazol-5-yl)methanone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Methyl-2-(2-Pyrazinyl)-1,3-Thiazole-5-Carbonyl Chloride | HCID 2776506 | — |
| Edukt | 3-(3-ethoxy-4-methoxyphenyl)-5,6-dihydro4H-pyridazine | HCID 11593854 | — |
| Produkt | 1-[3-(3-ethoxy-4-methoxyphenyl)-5,6-dihydro-4H-pyridazin-1-yl]-1-(4-methyl-2-pyrazin-2-yl-thiazol-5-yl)methanone | HCID 10365797 | 86,4% |
Reaktionsschritte
Analogously to Example 2, reaction of 300 mg of 3-(3-ethoxy-4-methoxyphenyl)-5,6-dihydro-4H-pyridazine with 307 mg of 4-methyl-2-pyrazin-2-yl-thiazole-5-carbonyl chloride (“BC”) gives the compound 1-[3-(3-ethoxy-4-methoxyphenyl)-5,6-dihydro-4H-pyridazin-1-yl]-1-(4-methyl-2-pyrazin-2-yl-thiazol-5-yl)methanone (484 mg, HPLC-MS m/e 438).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07790723B2 |
| Quelldatensatz | uspto-grants-2010_09 |
| ORD ID | ord-fe4e1cfeb79b4b258d567e6be083a9ee |
| Quellennotiz | uspto-grants-2010_09 |