Tert-butyl 4-(5-amino-2-methoxyphenyl)piperazine-1-carboxylate → 5-Difluoromethoxy-2-methoxy-N-(4-methoxy-3-piperazin-1-yl-phenyl)-benzene-sulfonamide Hydrochloride

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Tert-butyl 4-(5-amino-2-methoxyphenyl)piperazine-1-carboxylate	HCID 10686178	—
Edukt	5-(Difluoromethoxy)-2-methoxybenzene-1-sulfonyl chloride	HCID 66521642	—
Produkt	5-Difluoromethoxy-2-methoxy-N-(4-methoxy-3-piperazin-1-yl-phenyl)-benzene-sulfonamide Hydrochloride	HCID 67095168	—

Reaktionsschritte

The compound was prepared as described for Example 1 by reaction of 4-(5-amino-2-methoxy-phenyl)-piperazine-1-carboxylic acid tert-butyl ester with commercially available 5-difluoromethoxy-2-methoxybenzenesulfonylchloride followed by deprotection under acidic conditions.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07790727B2
Quelldatensatz	uspto-grants-2010_09
ORD ID	ord-dc189945d9f14a92b24a50c026ecaa4d
Quellennotiz	uspto-grants-2010_09