(7-Chlorothieno[3,2-b]pyridin-2-yl)(pyrrolidin-1-yl)methanone → (7-(2-Fluoro-4-nitrophenoxy)thieno[3,2-b]pyridin-2-yl)(pyrrolidin-1-yl)methanone

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	(7-Chlorothieno[3,2-b]pyridin-2-yl)(pyrrolidin-1-yl)methanone	HCID 11173165	—
Edukt	7-(2-fluoro-4-nitrophenoxy)-N,N-dimethylthieno[3,2-b]pyridine-2-carboxamide	HCID 59424475	—
Produkt	(7-(2-Fluoro-4-nitrophenoxy)thieno[3,2-b]pyridin-2-yl)(pyrrolidin-1-yl)methanone	HCID 59424552	93%

Reaktionsschritte

Starting from (7-chlorothieno[3,2-b]pyridin-2-yl)(pyrrolidin-1-yl)methanone (139, scheme 26) and following the procedure described above for the synthesis of compound 6 (scheme 1, example 1), title compound 193 was obtained in (93% yield). LRMS (M+1) 387.4 (100%).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07790729B2
Quelldatensatz	uspto-grants-2010_09
ORD ID	ord-cb13b5d4da6946cfa07e3e27f4d009f2
Quellennotiz	uspto-grants-2010_09