Paclitaxel → Baccatin Iii

HRID 1712858

Reaktionsgleichung

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Komponenten

Edukt 2

HCID 36314Paclitaxel

HCID 1844927-Epi-Taxol

Produkt 1

HCID 65366Baccatin Iii

Versuchsvorschrift

Degradation products were formed in the same proportions as in the experiments conducted under room temperature but in significantly lower quantities. Again, 7-epi-taxol was the main degradation product of paclitaxel (10% at pH 8.0). Baccatin III and 10-deacethyltaxol were formed for about 5 to 6% at pH 8.0. Found unknown substances were the same.

Aufarbeitung

customDegradation products were formed in the same proportions as in the experiments
customconducted under room temperature but in significantly lower quantities

Quellen und Nachweise

ORD-Eintrag: ord-bf120b8d5e6843258c700d82d8baab17
Quelldatensatz: uspto-grants-2010_09
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US07794747B2

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