Butaclamol → Dopamine

HRID 1712869

Reaktionsgleichung

Reaktionsgleichung von HRID 1712869
C[N:2]1[CH2:12][C@H:11](C2C=CC=CC=2)[C:10]2[CH:9]=[C:8]([OH:19])[C:7](Cl)=[CH:6][C:5]=2CC1.CC([C@]1([OH:47])C[C@H]2N(C[C@H]3C4C2=CC=CC=4CCC2C=CC=CC3=2)CC1)(C)C>>[NH2:2][CH2:12][CH2:11][C:10]1[CH:5]=[CH:6][C:7]([OH:47])=[C:8]([OH:19])[CH:9]=1

Komponenten

3

Edukt 2

HCID 37461ButaclamolHCID 3036864R-(+)-8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepine-7-ol

Produkt 1

HCID 681Dopamine

Versuchsvorschrift

HEK cells were transfected with DNA encoding D1-NLS-GFP (2 micrograms), and D1-WT (6 micrograms) for 48 hours. These cells were treated 6 hrs after transfection with SCH-23390 (10 micromolar), or (+)butaclamol (10 micromolar). The medium containing antagonist was changed at 6, 22, 30 and 42 hours after transfection. Control cells received no antagonist treatment.

Aufarbeitung

  1. additionThe medium containing antagonist
  2. customwas changed at 6, 22, 30 and 42 hours

Quellen und Nachweise

ORD-Eintrag
ord-a3f9fc04036e44f4afbc9730448073af
Quelldatensatz
uspto-grants-2010_09
Patentnummer
US07794955B2

Verknüpfte Notizen

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