Hydrochloric Acid → HCID 66877005, Verbindung
Reaktionsgleichung
C([O:5][C:6](=[O:23])[CH2:7][N:8]1[CH2:17][C:16]2[N:15]=[CH:14][C:13]([C:18]([O:20][CH2:21][CH3:22])=[O:19])=[CH:12][C:11]=2[CH2:10][CH2:9]1)(C)(C)C.[ClH:24]>O1CCOCC1>[ClH:24].[CH2:21]([O:20][C:18]([C:13]1[CH:14]=[N:15][C:16]2[CH2:17][N:8]([CH2:7][C:6]([OH:23])=[O:5])[CH2:9][CH2:10][C:11]=2[CH:12]=1)=[O:19])[CH3:22]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
To a solution of ethyl 7-(2-tert-butoxy-2-oxoethyl)-5,6,7,8-tetrahydro-1,7-naphthyridine-3-carboxylate (657 mg, 2.05 mmol) in dioxane (10 mL) is added 4 N HCl in dioxane (5 ml, 20 mmol) and the mixture is stirred at rt overnight. The solvent is removed and the residue is washed with ether to give the title compound as a white solid. MS (M+1): 265.1.