4-(3-(Trifluoromethyl)phenoxy)piperidine → N-(3-Methylbutyl)-6-{4-[3-(trifluoromethyl)phenoxy]piperidin-1-yl}pyridazine-3-carboxamide
Reaktionsgleichung
Cl[C:2]1[N:7]=[N:6][C:5]([C:8]([NH:10][CH2:11][CH2:12][CH:13]([CH3:15])[CH3:14])=[O:9])=[CH:4][CH:3]=1.[F:16][C:17]([F:32])([F:31])[C:18]1[CH:19]=[C:20]([CH:28]=[CH:29][CH:30]=1)[O:21][CH:22]1[CH2:27][CH2:26][NH:25][CH2:24][CH2:23]1>>[CH3:14][CH:13]([CH3:15])[CH2:12][CH2:11][NH:10][C:8]([C:5]1[N:6]=[N:7][C:2]([N:25]2[CH2:24][CH2:23][CH:22]([O:21][C:20]3[CH:28]=[CH:29][CH:30]=[C:18]([C:17]([F:16])([F:31])[F:32])[CH:19]=3)[CH2:27][CH2:26]2)=[CH:3][CH:4]=1)=[O:9]Komponenten
3
Versuchsvorschrift
The title compound was prepared in the same manner as described for Example 16 from 6-chloro-N-(3-methylbutyl)pyridazine-3-carboxamide and 4-[3-(trifluoromethyl)phenoxy]piperidine. MS (+ESI) m/z 437 (MH+).
Quellen und Nachweise
- ORD-Eintrag
- ord-4ad3c9b6b41a42129698e12d1bb32812
- Quelldatensatz
- uspto-grants-2010_09
- Patentnummer
- US07799787B2
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