6-Methyl-1,2,3,4-tetrahydroquinoline → 2-(Benzo[d]thiazol-2-ylthio)-1-(6-methyl-3,4-dihydroquinolin-1(2H)-yl)ethanone
Reaktionsgleichung
[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[S:10][CH2:11][C:12]([OH:14])=O.[CH3:15][C:16]1[CH:17]=[C:18]2[C:23](=[CH:24][CH:25]=1)[NH:22][CH2:21][CH2:20][CH2:19]2>>[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[S:10][CH2:11][C:12]([N:22]1[C:23]2[C:18](=[CH:17][C:16]([CH3:15])=[CH:25][CH:24]=2)[CH2:19][CH2:20][CH2:21]1)=[O:14]Komponenten
3
Versuchsvorschrift
The title compound was synthesized according to General Procedure B using 2-(benzo[d]thiazol-2-ylthio)acetic acid and 6-methyl-1,2,3,4-tetrahydroquinoline to yield 38 (450.5 mg, 85%): MS (APCI): m/z 355 [M+H]+. Anal. Calcd. for C19H18N2OS2: C, 64.39; H, 5.12; N, 7.90. Found: C, 64.55; H, 5.01; N, 7.88.
Aufarbeitung
- customThe title compound was synthesized