3-(1H-Indol-7-yl)-N-methyl-3-phenyl-propionamide → HCID 57659795, Verbindung
Reaktionsgleichung
[CH2:1]([O:3][C:4](=[O:25])[CH:5]=[C:6]([C:13]1[CH:14]=[C:15]2[C:19](=[CH:20][CH:21]=1)[NH:18][C:17]([C:22](=[O:24])[NH2:23])=[CH:16]2)[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)[CH3:2].N1C2C(=CC=CC=2C(C2C=CC=CC=2)CC(NC)=O)C=C1>>[CH2:1]([O:3][C:4](=[O:25])[CH2:5][CH:6]([C:13]1[CH:14]=[C:15]2[C:19](=[CH:20][CH:21]=1)[NH:18][C:17]([C:22](=[O:24])[NH2:23])=[CH:16]2)[C:7]1[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=1)[CH3:2]Komponenten
3
Versuchsvorschrift
3-(2-Carbamoyl-1H-indol-5-yl)-3-phenyl-propionic acid ethyl ester CII (628 mg) was prepared from 3-(2-carbamoyl-1H-indol-5-yl)-3-phenyl-acrylic acid ethyl ester using the procedure described above for preparation of 3-(1H-Indol-7-yl)-N-methyl-3-phenyl-propionamide XIX (Example 4).
Quellen und Nachweise
- ORD-Eintrag
- ord-f184d2fafeee4abeb9932bd2045f7e37
- Quelldatensatz
- uspto-grants-2010_09