HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Phenylboronic Acid → 3-{3-[(6-Phenyl-pyridine-2-carbonyl)-amino]-phenyl}-propionic acid ethyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Phenylboronic Acid | HCID 66827 | — |
| Edukt | 3-(3-{[6-Bromo-pyridine-2-carbonyl)-amino]-phenyl}-propionic acid ethyl ester | HCID 59654822 | — |
| Produkt | 3-{3-[(6-Phenyl-pyridine-2-carbonyl)-amino]-phenyl}-propionic acid ethyl ester | HCID 59654842 | — |
Reaktionsschritte
The pyridyl bromide (161) (100 mg, 0.27 mmol) was coupled to phenylboronic acid (30 mg, 0.25 mmol) using Method E. The residue was purified by column chromatography eluting with 15% EtOAc in heptane to give the title compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07803841B2 |
| Quelldatensatz | uspto-grants-2010_09 |
| ORD ID | ord-1f82eb92fd3444ed96fb430f471dc65f |
| Quellennotiz | uspto-grants-2010_09 |