HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Aminocinnamic acid ethyl ester → 3-{3-[(6-Bromo-pyridine-2-carbonyl)-amino]-phenyl}-acrylic acid ethyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-Aminocinnamic acid ethyl ester | HCID 97825 | — |
| Edukt | 6-Bromopyridine-2-carboxylic acid | HCID 593919 | — |
| Produkt | 3-{3-[(6-Bromo-pyridine-2-carbonyl)-amino]-phenyl}-acrylic acid ethyl ester | HCID 72348809 | — |
Reaktionsschritte
Aniline (60) (124 mg, 0.6 mmol) was coupled to 6-bromo-pyridine-2-carboxylic acid (131 mg, 0.6 mmol) using Method C. The residue was purified by column chromatography eluting in 10% EtOAc in heptane to give the title compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07803841B2 |
| Quelldatensatz | uspto-grants-2010_09 |
| ORD ID | ord-68065a52403c42509ae9196cb07d873d |
| Quellennotiz | uspto-grants-2010_09 |